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Phenotypes Associated with This Genotype
Genotype
MGI:5432779
Allelic
Composition
Aprttm1Jat/Aprt+
Genetic
Background
involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aprttm1Jat mutation (1 available); any Aprt mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
renal/urinary system
• some heterozygotes display crystalline material in the renal pelvis at autopsy
• a small amount of DHA crystal material is found in kidneys of both sexes, with no significant difference between male and female mice at 7-14 or at 30-45 days of age
• however, no renal pathological changes are observed at any age


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory