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Phenotypes Associated with This Genotype
Genotype
MGI:5432573
Allelic
Composition		 Crisp4tm1(icre)Mpo/Crisp4tm1(icre)Mpo
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crisp4tm1(icre)Mpo mutation (0 available); any Crisp4 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
decreased testis weight ( J:185787 )
• testis weight is significantly lower than wild-type; epididymis weight is lower but not statistically significantly lower
• testis and epididymal histologies are not different than wild-type; sperm concentration is not different from wild-type and morphology and motility of spermatozoa are normal

reproductive system
decreased testis weight ( J:185787 )
• testis weight is significantly lower than wild-type; epididymis weight is lower but not statistically significantly lower
• testis and epididymal histologies are not different than wild-type; sperm concentration is not different from wild-type and morphology and motility of spermatozoa are normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory