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Phenotypes Associated with This Genotype
Genotype
MGI:5432003
Allelic
Composition		 Epas1tm1Mcs/Epas1tm1Mcs
Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Epas1tm1Mcs mutation (1 available); any Epas1 mutation (66 available)
Hif1atm3Rsjo mutation (3 available); any Hif1a mutation (50 available)
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:186085 )
N
• mice exhibit normal hematopoietic stem cell frequency
decreased erythroid progenitor cell number ( J:186085 )
• decreased frequency of CD71+/Ter119+ cells in the bone marrow

skeleton

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory