Phenotypes for Kcnq1ot1 Meox2 MGI:5431828 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Kcnq1ot1^tm2.1Ckan/Kcnq1ot1⁺ Meox2^tm1(cre)Sor/Meox2⁺
Genetic Background	involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * SD7

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnq1ot1^tm2.1Ckan mutation (0 available); any Kcnq1ot1 mutation (0 available)
Meox2^tm1(cre)Sor mutation (3 available); any Meox2 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal imprinting ( J:185569 )

• loss of imprinting of ubiquitously imprinted genes when the Kcnq1ot1 allele is inherited paternally

• no alteration of imprinting status when the Kcnq1ot1 allele is inherited maternally

growth/size/body

decreased body weight ( J:185569 )

• at 4 weeks of age when the Kcnq1ot1 allele is inherited maternally

postnatal growth retardation ( J:185569 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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