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Phenotypes Associated with This Genotype
Genotype
MGI:5430905
Allelic
Composition		 Pkhd1tm1Som/Pkhd1tm1Som
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkhd1tm1Som mutation (0 available); any Pkhd1 mutation (222 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
cellular phenotype ( J:185863 )
N
• low apoptosis rates of the cells of the medullary collecting ducts of the kidney
abnormal mitotic spindle morphology ( J:185863 )
• loss of orientation of cell division to the lumen of the medullary collecting ducts of the kidney

renal/urinary system
renal/urinary system phenotype ( J:185863 )
N
• no cyst formation in the kidney
abnormal kidney epithelium morphology ( J:185863 )
• more interrupted pattern of dividing cells than seen in controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory