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Phenotypes Associated with This Genotype
Genotype
MGI:5430318
Allelic
Composition		 Gja1tm4Gfi/Gja1tm4Gfi
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja1tm4Gfi mutation (0 available); any Gja1 mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal heart rate ( J:185692 )
• resistant to electrical induction of ventricular tachycardia as occurs in controls
abnormal impulse conducting system conduction ( J:185692 )
• conduction velocities preserved after transverse aortic constriction unlike controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory