Phenotypes Associated with This Genotype

Genotype
MGI:5429515

• Allelic Composition: Dhrs4^tm1Lex/Dhrs4^tm1Lex
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal humoral immune response ( J:171883 )

• decreased mean serum IgG2a response to ovalbumin challenge when compared with that of controls

decreased IgG2a level ( J:171883 )

behavior/neurological

behavioral despair ( J:171883 )

• female mutants exhibited an increased depressive-like response during tail suspension testing

hematopoietic system

decreased IgG2a level ( J:171883 )