Phenotypes for Cd22 MGI:5429184 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cd22^m1Btlr/Cd22^m1Btlr
Genetic Background	involves: C57BL/6J

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd22^m1Btlr mutation (1 available); any Cd22 mutation (63 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:185495 )

N	• mice exhibit a normal response to recombinant Semliki Forest virus (SFV) encoded antigen

abnormal B cell differentiation ( J:185495 )

• partial block

decreased IgM level ( J:185495 )

• following NP-Ficoll immunization

hematopoietic system

abnormal B cell differentiation ( J:185495 )

• partial block

decreased IgM level ( J:185495 )

• following NP-Ficoll immunization

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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