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Phenotypes Associated with This Genotype
Genotype
MGI:5428928
Allelic
Composition
Acp1tm1Lex/Acp1tm1Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acp1tm1Lex mutation (1 available); any Acp1 mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• female mutant mice show an increased mean skin fibroblast proliferation rate

growth/size/body
• male homozygous mutant mice were notably smaller than their gender-matched control littermates

immune system
• homozygous mutant mice exhibit an increased mean serum IL-6 response to LPS challenge when compared with that of controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory