Analysis Tools
normal phenotype
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• Background Sensitivity: homozygous mice are viable and fertile, and exhibit normal heart and blood vessel formation; in addition, no differences were seen on a congenic C57BL/6 genetic background
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cardiovascular system
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N |
• in adult homozygous mice, cardiac function, capillary density, expression of key cardiac fetal and angiogenic genes, epicardial marker expression, and extracellular matrix deposition were indistinguishable from that of controls
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