Phenotypes for Gata4 Tg(Nkx2-5-cre)9Eno MGI:5427940 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gata4^tm1Grg/Gata4^tm1.1Wtp Tg(Nkx2-5-cre)9Eno/0
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata4^tm1.1Wtp mutation (0 available); any Gata4 mutation (37 available)
Gata4^tm1Grg mutation (1 available); any Gata4 mutation (37 available)
Tg(Nkx2-5-cre)9Eno mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Growth retardation and myocardial thinning in Gata4^tm1.1Wtp/Gata4^tm1Grg Tg(Nkx2-5-cre)9Eno/0 mice

mortality/aging

embryonic lethality during organogenesis, incomplete penetrance ( J:185124 )

• at E10.5

growth/size/body

embryonic growth retardation ( J:185124 )

• severe

cardiovascular system

thin myocardium ( J:185124 )

embryo

embryonic growth retardation ( J:185124 )

• severe

muscle

thin myocardium ( J:185124 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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