Phenotypes for Znrf3 MGI:5427834 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Znrf3^tm1.1Fcon/Znrf3^tm1.1Fcon
Genetic Background	involves: 129 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Znrf3^tm1.1Fcon mutation (0 available); any Znrf3 mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• mice die around birth

vision/eye

abnormal optic placode morphology ( J:184507 )

• at E10.5, mice fail to exhibit thickening and invagination of lens placode compared with wild-type mice

aphakia ( J:184507 )

nervous system

abnormal neural tube closure ( J:184507 )

• in some mice

embryo

abnormal neural tube closure ( J:184507 )

• in some mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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