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Phenotypes Associated with This Genotype
Genotype
MGI:5427700
Allelic
Composition
Msx2tm1Rilm/Msx2tm1Rilm
Tg(Pax6-cre,GFP)1Pgr/0
Genetic
Background
involves: 129S4/SvJae * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Msx2tm1Rilm mutation (1 available); any Msx2 mutation (26 available)
Tg(Pax6-cre,GFP)1Pgr mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• at E12.5, the cornea and lens are not separated
• at E12.5, the neural crest cells migrate into the vitreous cavity and push the lens toward the cornea while in wild-type mice, the lens vesicle and surface ectoderm are completely separated


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory