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Phenotypes Associated with This Genotype
Genotype
MGI:5427614
Allelic
Composition		 \Hormad2tm1Atot/\Hormad2tm1Atot
\Spo11tm1Mjn/\Spo11tm1Mjn
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6JOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hormad2tm1Atot mutation (0 available); any Hormad2 mutation (33 available)
Spo11tm1Mjn mutation (2 available); any Spo11 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:183982 )
N
• oocyte numbers are similar to wild-type females
abnormal meiosis ( J:183982 )
• significant decrease in the frequency of pseudo-sex bodies compared to mutant mice wild-type for Hormad2

cellular
abnormal meiosis ( J:183982 )
• significant decrease in the frequency of pseudo-sex bodies compared to mutant mice wild-type for Hormad2

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory