Phenotypes for Agrp Grin1 MGI:5427451 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Agrp^{tm2(HBEGF)Rpa}/Agrp⁺ Grin1^tm2Stl/Grin1^tm2Stl
Genetic Background	involves: 129S4/SvJae * 129S4/SvJaeSor

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agrp^{tm2(HBEGF)Rpa} mutation (1 available); any Agrp mutation (20 available)
Grin1^tm2Stl mutation (1 available); any Grin1 mutation (64 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal eating behavior ( J:182577 )

• diphtheria-treated mice bilaterally injected with a virus expressing a AAV1-CreGFP into the parabrachial nucleus

growth/size/body

abnormal postnatal growth/weight/body size ( J:182577 )

• diphtheria-treated mice injected with a virus expressing a AAV1-CreGFP into the nucleus tractus solitaries or parabrachial nucleus prevents starvation induced by AgRP neuron ablation unlike in control mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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