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Phenotypes Associated with This Genotype
Genotype
MGI:5427451
Allelic
Composition		 Agrptm2(HBEGF)Rpa/Agrp+
Grin1tm2Stl/Grin1tm2Stl
Genetic
Background		 involves: 129S4/SvJae * 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agrptm2(HBEGF)Rpa mutation (1 available); any Agrp mutation (18 available)
Grin1tm2Stl mutation (1 available); any Grin1 mutation (64 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal eating behavior ( J:182577 )
• diphtheria-treated mice bilaterally injected with a virus expressing a AAV1-CreGFP into the parabrachial nucleus

growth/size/body
abnormal postnatal growth/weight/body size ( J:182577 )
• diphtheria-treated mice injected with a virus expressing a AAV1-CreGFP into the nucleus tractus solitaries or parabrachial nucleus prevents starvation induced by AgRP neuron ablation unlike in control mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory