About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5427442
Allelic
Composition		 Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi
Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic
Background		 involves: C57BL/6N * C57BL/6NCrj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pik3c3tm1c(EUCOMM)Wtsi mutation (1 available); any Pik3c3 mutation (48 available)
Tg(CAG-EGFP/Map1lc3b)53Nmz mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal autophagy ( J:182628 )
• fed and nutrient-starved conditions mouse embryonic fibroblasts transduced with a cre-expressing adenovirus exhibit blocked autophagy flux unlike control cells

homeostasis/metabolism
abnormal autophagy ( J:182628 )
• fed and nutrient-starved conditions mouse embryonic fibroblasts transduced with a cre-expressing adenovirus exhibit blocked autophagy flux unlike control cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory