Phenotypes Associated with This Genotype

Genotype
MGI:5427095

• Allelic Composition: Del(16Lipi-Usp25)1Dja/Del(16Lipi-Usp25)1Dja
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Small size and increased apoptosis in Del(16Lipi-Usp25)1Dja/Del(16Lipi-Usp25)1Dja embryos

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:184302 )

• mice die on or before E10.5

nervous system

increased neural tube apoptosis ( J:184302 )

• at E10.5, embryos exhibit increased apoptotic cells in the neural tube compared with wild-type mice

growth/size/body

decreased embryo size ( J:184302 )

• at E10.5

embryo

decreased embryo size ( J:184302 )

• at E10.5

cellular

increased neural tube apoptosis ( J:184302 )

• at E10.5, embryos exhibit increased apoptotic cells in the neural tube compared with wild-type mice