Phenotypes Associated with This Genotype

Genotype
MGI:5426978

• Allelic Composition: Pbx1^tm1.1Koss/Pbx1^tm1.2Koss; Tmem163^{Tg(ACTB-cre)2Mrt}/0
• Genetic Background: involves: 129P2/OlaHsd * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

absent spleen ( J:184521 )

skeleton

abnormal humerus morphology ( J:184521 )

• phenotype duplicates that of global null mice

• fusion of the glenoid cavity of the scapula to the humeral head

• partial duplication of the head

abnormal deltoid tuberosity morphology ( J:184521 )

• detached

abnormal scapula morphology ( J:184521 )

• fusion of the glenoid cavity to the humeral head

scapular bone hypoplasia ( J:184521 )

• thin and hypoplastic

abnormal rib morphology ( J:184521 )

• phenotype duplicates that of global null mice

• truncated, dysmorphic, and occasionally fused ribs

rib fusion ( J:184521 )

• occasional

short ribs ( J:184521 )

• truncated

immune system

absent spleen ( J:184521 )

limbs/digits/tail

abnormal humerus morphology ( J:184521 )

• phenotype duplicates that of global null mice

• fusion of the glenoid cavity of the scapula to the humeral head

• partial duplication of the head

abnormal deltoid tuberosity morphology ( J:184521 )

• detached