Phenotypes Associated with This Genotype

Genotype
MGI:5426940

• Allelic Composition: Ctnnb1^tm1Yy/Ctnnb1^tm1Yy; Tg(Prrx1-cre)1Cjt/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

abnormal limb development ( J:184918 )

• authors state that mice exhibit the same defects as in Wls^tm1Xzg/Wls^tm1Xzg Tg(Msx2-cre)5Rem mice

integument

abnormal hair follicle development ( J:184918 )

• loss of hair follicles in the dorsal dermis of the limb

muscle

abnormal tendon morphology ( J:184918 )

• in the forelimbs at E17.5

skeleton

abnormal tendon morphology ( J:184918 )

• in the forelimbs at E17.5

abnormal ligament morphology ( J:184918 )

• in the forelimbs at E17.5

pigmentation

abnormal melanogenesis ( J:184918 )

• loss of melanogenesis in the dorsal dermis of the limb