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Phenotypes Associated with This Genotype
Genotype
MGI:5318688
Allelic
Composition		 Chrnb2tm1Jpc/Chrnb2tm1Jpc
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chrnb2tm1Jpc mutation (0 available); any Chrnb2 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
myeloid hyperplasia ( J:140280 )
• increased numbers of early myeloid cells in bone marrow
decreased erythroblast number ( J:140280 )
• fewer mature erythroid cells (normoblasts) found in bone marrow

immune system
myeloid hyperplasia ( J:140280 )
• increased numbers of early myeloid cells in bone marrow

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory