Phenotypes Associated with This Genotype

Genotype
MGI:5318592

• Allelic Composition: Rhag^tm1Goo/Rhag^tm1Goo
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal erythrocyte physiology ( J:182122 )

• the alkalinisation rate constant values for ghosts are reduced by 70-85% compared to wild-type red blood cells

• basal adhesion to bEnd.3 endothelial cells is reduced

homeostasis/metabolism

abnormal blood homeostasis ( J:182122 )

♂ • decreased transferrin levels in males at 17 weeks of age

increased circulating iron level ( J:182122 )

• slightly increased at 17 weeks of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	Rh deficiency syndrome	DOID:0050641	OMIM:268150	J:182122