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Phenotypes Associated with This Genotype
Genotype
MGI:5318590
Allelic
Composition		 Rhdtm1Goo/Rhdtm1Goo
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhdtm1Goo mutation (2 available); any Rhd mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal erythrocyte physiology ( J:182122 )
• the alkalinisation rate constant values for ghosts are reduced by 30-40% compared to wild-type red blood cells
• basal adhesion to bEnd.3 endothelial cells is reduced

homeostasis/metabolism
increased circulating iron level ( J:182122 )
• slightly increased at 17 weeks of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory