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Phenotypes Associated with This Genotype
Genotype
MGI:5318569
Allelic
Composition		 Gt(ROSA)26Sortm1(Thy1-FBXL2)Wata/Gt(ROSA)26Sor+
Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/0
Genetic
Background		 involves: C57BL/6 * C57BL/6N * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Thy1-FBXL2)Wata mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
amyloid beta deposits ( J:182731 )
• mice exhibit a reduction in amyloid plaques compared with Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte mice

homeostasis/metabolism
amyloid beta deposits ( J:182731 )
• mice exhibit a reduction in amyloid plaques compared with Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory