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Phenotypes Associated with This Genotype
Genotype
MGI:5318047
Allelic
Composition		 Wnk3tm1.1Esoh/Wnk3tm1.1Esoh
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnk3tm1.1Esoh mutation (0 available); any Wnk3 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased systemic arterial blood pressure ( J:181538 )
• when fed a low-salt diet
• however, mice exhibit normal blood pressure when fed standard chow

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:181538 )
N
• mice exhibit normal blood and urine homeostasis even when fed a low-salt or high-salt diet

renal/urinary system
renal/urinary system phenotype ( J:181538 )
N
• mice exhibit normal blood and urine homeostasis even when fed a low-salt or high-salt diet

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory