About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5317872
Allelic
Composition
Pax6tm1.2Xzh/Pax6tm1.2Xzh
Genetic
Background
B6.129S6-Pax6tm1.2Xzh
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax6tm1.2Xzh mutation (0 available); any Pax6 mutation (90 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• hypoplastic
• the lens remains attached to the overlying surface ectoderm
• complete lens degeneration at P6
• the posterior lens fiber fails to rise up to the anterior lens epithelium
• the retinal pigmented epithelium of the optic cup presents with an optic coloboma
• conspicuously smaller at E14.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory