Phenotypes for Runx1 MGI:5316039 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Runx1^{tm2.1(cre/Esr1)Ims}/Runx1^{tm2.1(cre/Esr1)Ims}
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Runx1^{tm2.1(cre/Esr1*)Ims} mutation (0 available); any Runx1 mutation (35 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:182232 )

• all embryos die around E12.5

hematopoietic system

anemia ( J:182232 )

• embryos exhibit severe liver anemia

cardiovascular system

hemorrhage ( J:182232 )

• embryos display a severe hemorrhagic phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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