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Phenotypes Associated with This Genotype
Genotype
MGI:5314604
Allelic
Composition
Tg(CAG-cat,-TBX3)1Vmc/0
Tg(Myh6-cre)2182Mds/0
Genetic
Background
involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CAG-cat,-TBX3)1Vmc mutation (0 available)
Tg(Myh6-cre)2182Mds mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• mice exhibit hypoplastic chamber walls with reduced cellular proliferation in the ventricular walls compared to in control mice
• mice exhibit a subendocardial space near the atrioventricular cushions filled with mesenchymal cells unlike in control mice
• mice exhibit abnormal cardiac jelly and cushion formation in chamber myocardium compared with control mice

muscle
• mice exhibit hypoplastic chamber walls with reduced cellular proliferation in the ventricular walls compared to in control mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory