Phenotypes Associated with This Genotype

Genotype
MGI:5313810

• Allelic Composition: b2b251Clo/b2b251Clo
• Genetic Background: C57BL/6J-b2b251Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Malalignment of the great arteries suggest double outlet right ventricle (DORV) in mutant 251-007-1 (E15.5), which was subsequently confirmed by EFIC imaging.

cardiovascular system

abnormal aortic arch morphology ( J:175213 )

• hypoplastic transverse arch seen in one mutant

aorta coarctation ( J:175213 )

aorta tubular hypoplasia ( J:175213 )

double outlet right ventricle ( J:175213 )

overriding aortic valve ( J:175213 )

perimembraneous ventricular septal defect ( J:175213 )

inlet ventricular septal defect ( J:175213 )

respiratory system

abnormal lung morphology ( J:175213 )

lung cyst ( J:175213 )

growth/size/body

lung cyst ( J:175213 )