Mouse Genome Informatics
tg
    Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/0
C57BL/6-Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• mutants develop amyloid plaques over time that increase in size, with the highest rate of new plaque appearance in mice between 4 and 5 months of age
• newly formed plaques and preexisting plaques grow at similar rates

homeostasis/metabolism
• mutants develop amyloid plaques over time that increase in size, with the highest rate of new plaque appearance in mice between 4 and 5 months of age
• newly formed plaques and preexisting plaques grow at similar rates

Mouse Models of Human Disease
OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:180835