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Phenotypes Associated with This Genotype
Genotype
MGI:5313530
Allelic
Composition
Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/0
Genetic
Background
C57BL/6-Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mutants develop amyloid plaques over time that increase in size, with the highest rate of new plaque appearance in mice between 4 and 5 months of age
• newly formed plaques and preexisting plaques grow at similar rates

homeostasis/metabolism
• mutants develop amyloid plaques over time that increase in size, with the highest rate of new plaque appearance in mice between 4 and 5 months of age
• newly formed plaques and preexisting plaques grow at similar rates

Mouse Models of Human Disease
OMIM ID Ref(s)
Alzheimer Disease; AD 104300 J:180835


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory