Phenotypes for Irf8 MGI:5313306 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Irf8^tm1Hor/Irf8^tm1Hor
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irf8^tm1Hor mutation (1 available); any Irf8 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal humoral immune response ( J:181366 )

• coupling antigen to anti-Clec9a antibody fails to enhance antibody response

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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