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Phenotypes Associated with This Genotype
Genotype
MGI:5308974
Allelic
Composition		 Cdx1tm1Pgr/Cdx1tm1Pgr
Cdx2tm2Fbe/Cdx2tm2Fbe
Tg(Cyp1a1-cre/ERT)1Dwi/0
Genetic
Background		 involves: 129 * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx1tm1Pgr mutation (1 available); any Cdx1 mutation (16 available)
Cdx2tm2Fbe mutation (0 available); any Cdx2 mutation (22 available)
Tg(Cyp1a1-cre/ERT)1Dwi mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
abnormal crypts of Lieberkuhn morphology ( J:179732 )
• cystic vesicles appear 1 week after treatment with tamoxifen and BNF, earlier than in mutant mice wild-type for Cdx1

endocrine/exocrine glands
abnormal crypts of Lieberkuhn morphology ( J:179732 )
• cystic vesicles appear 1 week after treatment with tamoxifen and BNF, earlier than in mutant mice wild-type for Cdx1

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory