Phenotypes for Casr Tg(Col2a1-cre/ERT)KA3Smac MGI:5306894 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Casr^tm1Wch/Casr^tm1Wch Tg(Col2a1-cre/ERT)KA3Smac/0
Genetic Background	involves: 129S4/SvJae * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Casr^tm1Wch mutation (0 available); any Casr mutation (60 available)
Tg(Col2a1-cre/ERT)KA3Smac mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal skeleton development ( J:180651 )

• tamoxifen-treated mice exhibit reduced skeleton length compared with control mice

increased width of hypertrophic chondrocyte zone ( J:180651 )

• in tamoxifen-treated mice

decreased bone mineralization ( J:180651 )

• decreased mineralization in tamoxifen-treated mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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