Phenotypes Associated with This Genotype

Genotype
MGI:5306892

• Allelic Composition: Casr^tm1Wch/Casr^tm1Wch; Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
• Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

skeleton phenotype ( J:180651 )

N • mice exhibit normal cortical bone thickness

decreased compact bone volume ( J:180651 )

abnormal trabecular bone morphology ( J:180651 )

• mice exhibit increased trabecular spacing compared with control mice

decreased trabecular bone volume ( J:180651 )

decreased bone trabecula number ( J:180651 )

decreased trabecular bone connectivity density ( J:180651 )

decreased trabecular bone thickness ( J:180651 )

abnormal skeleton development ( J:180651 )

• blocked, reduced bone formation

decreased bone mineralization ( J:180651 )

• undermineralized skeleton

growth/size/body

decreased body size ( J:180651 )

postnatal growth retardation ( J:180651 )

• blocked