About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5305730
Allelic
Composition
Fgf23tm1.1Kew/Fgf23tm1.1Kew
Genetic
Background
B6.129-Fgf23tm1.1Kew
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf23tm1.1Kew mutation (0 available); any Fgf23 mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Fgf23tm1.1Kew/Fgf23tm1.1Kew mice fed a low-iron diet exhibit osteomalacia

skeleton
• mice fed a low-iron diet exhibit osteocytic lesions in the cortical bone proximal to the metaphysis unlike wild-type mice (J:180061)
• mice fed a low-iron diet exhibit osteocytic lesions in the cortical bone proximal to the metaphysis unlike wild-type mice (J:180061)
• osteoid surface to bone surface is increased 9-fold in mice fed a low-iron diet compared with wild-type mice (J:180061)
• osteoid surface to bone surface is increased 9-fold in mice fed a low-iron diet compared with wild-type mice (J:180061)
• in mice fed a low-iron diet (J:180061)
• in mice fed a low-iron diet (J:180061)
• in the cancellous bone of mice fed a low-iron diet (J:180061)
• in the cancellous bone of mice fed a low-iron diet (J:180061)

homeostasis/metabolism
• on a low-iron diet at 8 and 12 weeks (J:180061)
• on a low-iron diet at 8 and 12 weeks (J:180061)
• on a low-iron diet at 8 and 12 weeks (J:180061)
• on a low-iron diet at 8 and 12 weeks (J:180061)
• erum vitamin D levels are decreased in mice fed a low-iron diet compared with wild-type mice (J:180061)
• erum vitamin D levels are decreased in mice fed a low-iron diet compared with wild-type mice (J:180061)

Mouse Models of Human Disease
OMIM ID Ref(s)
Hypophosphatemic Rickets, Autosomal Dominant; ADHR 193100 J:180061


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory