Mouse Genome Informatics
hm
    Fgf23tm1.1Kew/Fgf23tm1.1Kew
B6.129-Fgf23tm1.1Kew
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       

Fgf23tm1.1Kew/Fgf23tm1.1Kew mice fed a low-iron diet exhibit osteomalacia

skeleton
• mice fed a low-iron diet exhibit osteocytic lesions in the cortical bone proximal to the metaphysis unlike wild-type mice
• osteoid surface to bone surface is increased 9-fold in mice fed a low-iron diet compared with wild-type mice
• in mice fed a low-iron diet
• in the cancellous bone of mice fed a low-iron diet

homeostasis/metabolism
• on a low-iron diet at 8 and 12 weeks
• on a low-iron diet at 8 and 12 weeks
• erum vitamin D levels are decreased in mice fed a low-iron diet compared with wild-type mice

Mouse Models of Human Disease
OMIM IDRef(s)
Hypophosphatemic Rickets, Autosomal Dominant; ADHR 193100 J:180061