Analysis Tools
nervous system
astrocytosis
(
J:179356
)
|
• in the upper half of the neocortex
|
|
• radial glial cells are disrupted during neocortical development
• radial glial cell processes extend beyond the disruptions of the pial basement membrane
|
|
• mice exhibit lamination defects with an indistinct layer I unlike in wild-type mice
• the two cerebral hemispheres are fused
• layers II/III, IV, V, and VI cannot be identified
|
|
• Cajal-Retzius cells are disrupted during neocortical development
• unlike in wild-type mice, Cajal-Retzius cells are located between the diffuse cell zone and the cortical plate
• in some regions Cajal-Retzius cells are absent in some regions
|
|
• 2 mice exhibit lamination defects of pyramidal cells in all CA fields of the Ammon's horn with some pyramidal neurons displaced
|
|
• 10 of 13 mice exhibit dispersion of CA3 of the Ammon's horn with CA3 cells
|
|
• wavy inferior blade
|
|
• lamination defects
|
|
• mice exhibit ectopic fibroblasts in the upper half of the neocortex
|
cellular
astrocytosis
(
J:179356
)
|
• in the upper half of the neocortex
|
|
• radial glial cells are disrupted during neocortical development
• radial glial cell processes extend beyond the disruptions of the pial basement membrane
|
|
• the pial basement membrane and glia limitans are disrupted during development and in adult mice compared to in wild-type mice
|
