Phenotypes Associated with This Genotype

Genotype
MGI:5301621

• Allelic Composition: Atxn1l^tm2.1Hzo/Atxn1l^tm2.1Hzo
• Genetic Background: B6.129S7-Atxn1l^tm2.1Hzo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:178303 )

• about 50% of mice die before P21

nervous system

hydrocephaly ( J:178303 )

• about 30% of surviving mice develop hydrocephalus

behavior/neurological

lethargy ( J:178303 )

• develops in symptomatic mice between 1 and 4 weeks of age

growth/size/body

decreased body size ( J:178303 )

cachexia ( J:178303 )

• emaciation develops in symptomatic mice between 1 and 4 weeks of age

skeleton

domed cranium ( J:178303 )

• develops in symptomatic mice between 1 and 4 weeks of age

kyphosis ( J:178303 )

• develops in symptomatic mice between 1 and 4 weeks of age

craniofacial

domed cranium ( J:178303 )

• develops in symptomatic mice between 1 and 4 weeks of age