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Phenotypes Associated with This Genotype
Genotype
MGI:5297948
Allelic
Composition
Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+
Ntstm1(cre)Mgmj/Nts+
Genetic
Background
involves: 129S4/SvJaeSor * C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2Sho mutation (2 available); any Gt(ROSA)26Sor mutation (935 available)
Ntstm1(cre)Mgmj mutation (1 available); any Nts mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• 62% of brain slice lateral hypothalamic area (LHA) Nts +ve neurons depolarize when treated with leptin while about 20% of Nts +ve neurons respond with slow hyperpolarization


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory