vision/eye
• mice exhibit extraneous amorphous tissue between the retina and the lens unlike in wild-type mice
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• 2 of 18 mice exhibit swelling of the optic nerve, which disrupts the outer nuclear layer of the retina
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• one mouse exhibits hypoplastic ciliary muscle compared with wild-type mice
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• 6 of 10 mice exhibit reduced angle between cornea and iris compared with wild-type mice
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• smaller in 7 of 10 mice
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• absent in 2 of 10 mice
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• in 7 of 10 mice
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• hypoplastic ciliary body or ciliary body process
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• hypoplastic ciliary body or ciliary body process
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• the iris stroma sows irregular thinning of the tissue and loss of structural organization at P45
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• iridocorneal adhesion is present
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exophthalmos
(
J:178103
)
• in two mice at 6 months of age
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• disrupted in 2 of 18 mice due to swelling of the optic nerve
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nervous system
• 2 of 18 mice exhibit swelling of the optic nerve, which disrupts the outer nuclear layer of the retina
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homeostasis/metabolism
• 2 of 18 mice exhibit swelling of the optic nerve, which disrupts the outer nuclear layer of the retina
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muscle
• one mouse exhibits hypoplastic ciliary muscle compared with wild-type mice
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