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Phenotypes Associated with This Genotype
Genotype
MGI:5297378
Allelic
Composition		 Tnfsf11tm1.1Caob/Tnfsf11tm1.1Caob
Tg(BGLAP-cre)1Clem/0
Genetic
Background		 involves: 129S * 129X1/SvJ * C57BL/6 * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(BGLAP-cre)1Clem mutation (1 available)
Tnfsf11tm1.1Caob mutation (1 available); any Tnfsf11 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
failure of tooth eruption ( J:177558 )
• in some mice
increased bone mineral density ( J:177558 )
• at 5 weeks of age
increased trabecular bone volume ( J:177558 )
• at 5 weeks of age
abnormal cartilage morphology ( J:177558 )
• mice exhibit unresorbed cartilage unlike wild-type mice
increased long bone epiphyseal plate size ( J:177558 )
• widened growth plate in the femur

craniofacial
failure of tooth eruption ( J:177558 )
• in some mice

growth/size/body
failure of tooth eruption ( J:177558 )
• in some mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory