Phenotypes Associated with This Genotype

Genotype
MGI:5297172

• Allelic Composition: Tg(CAG-mRFP1,-SOX9,-EGFP)1Haak/0; Tg(Col2a1-cre)1Bhr/0
• Genetic Background: involves: C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal endochondral bone ossification ( J:176952 )

• delay in formation of primary ossification centers in forelimb skeletal elements is observed in E17.5 embryos

abnormal chondrocyte physiology ( J:176952 )

• delayed hypertrophic conversion of proliferating chondrocytes is seen in E15.5 embryos

limbs/digits/tail

abnormal forelimb morphology ( J:176952 )

• an expansion of the hypertrophic zone of in forelimb skeletal elements in observed in E17.5 embryos