About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5296041
Allelic
Composition		 Map3k10tm1Dsd/Map3k10tm1Dsd
Map3k11tm1Rjd/Map3k11tm1Rjd
Genetic
Background		 involves: 129 * 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k10tm1Dsd mutation (0 available); any Map3k10 mutation (34 available)
Map3k11tm1Rjd mutation (0 available); any Map3k11 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal circulating cytokine level ( J:177426 )
• suppression of LPS induced inflammatory cytokine production
abnormal circulating chemokine level ( J:177426 )
• suppression of LPS induced inflammatory chemokine production
abnormal response to infection ( J:177426 )
• suppression of LPS induced inflammatory cytokine and chemokine production

homeostasis/metabolism
abnormal circulating cytokine level ( J:177426 )
• suppression of LPS induced inflammatory cytokine production
abnormal circulating chemokine level ( J:177426 )
• suppression of LPS induced inflammatory chemokine production

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory