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Phenotypes Associated with This Genotype
Genotype
MGI:5296037
Allelic
Composition
Trpc6tm1Lbi/Trpc6tm1Lbi
Genetic
Background
involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trpc6tm1Lbi mutation (1 available); any Trpc6 mutation (68 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• at one light intensity, intrinsically photosensitive retinal ganglion cells exhibit enhanced spike activity compared with wild-type cells
• M1 and M2 intrinsically photosensitive retinal ganglion cells exhibit reduced amplitude of response to light stimulation and inward current compared to in wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory