Phenotypes for Ap2b1 MGI:5295994 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ap2b1^{Tg(Tyr)427Ove}/Ap2b1^{Tg(Tyr)427Ove}
Genetic Background	FVB/NJ-Ap2b1^{Tg(Tyr)427Ove}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ap2b1^{Tg(Tyr)427Ove} mutation (1 available); any Ap2b1 mutation (72 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal palatal shelf fusion at midline ( J:177760 )

• despite evidence of palatal shelf elevation, shelves fail to fuse at E17 and E18

cleft palate ( J:177760 )

digestive/alimentary system

abnormal palatal shelf fusion at midline ( J:177760 )

• despite evidence of palatal shelf elevation, shelves fail to fuse at E17 and E18

cleft palate ( J:177760 )

growth/size/body

abnormal palatal shelf fusion at midline ( J:177760 )

• despite evidence of palatal shelf elevation, shelves fail to fuse at E17 and E18

cleft palate ( J:177760 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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