Phenotypes for Ret MGI:5295936 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ret^tm1Cos/Ret⁺
Genetic Background	involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ret^tm1Cos mutation (2 available); any Ret mutation (52 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

renal/urinary system

decreased renal glomerulus number ( J:117753 )

• at P15, heterozygotes show a reduced mean glomerular density relative to wild-type littermates (7.25 versus 8.95 glomeruli per unit area, respectively)

single kidney ( J:117753 )

• at P15, about 4% of heterozygotes exhibit unilateral renal agenesis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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