Analysis Tools
nervous system
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• however, axon regeneration is normal
• remyelination following nerve crush injury is delayed compared to in wild-type mice
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• mice exhibit a transient delay in myelination compared with wild-type mice
• the sciatic nerve is hypomyelinated at P1, P3, and P5
• at P21 and P28, mice exhibit extensive outfoldings in compact myelin located in close vicinity to the paranode
• following nerve crush injury, mice exhibit reduced myelination compared with wild-type mice
• however, mice exhibit normal myelination at P7 and remyelination following nerve crush injury after 28 days
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• at P21 and P28
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homeostasis/metabolism
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• however, axon regeneration is normal
• remyelination following nerve crush injury is delayed compared to in wild-type mice
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behavior/neurological
| N |
• mice exhibit normal function on a rotarod, grip strength, and thermal nociception
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