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Phenotypes Associated with This Genotype
Genotype
MGI:5295294
Allelic
Composition		 Ireb2tm1Roua/Ireb2tm1Roua
Genetic
Background		 B6.Cg-Ireb2tm1Roua
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ireb2tm1Roua mutation (1 available); any Ireb2 mutation (64 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased spleen iron level ( J:176655 )
• decrease in nonheme iron

homeostasis/metabolism
decreased spleen iron level ( J:176655 )
• decrease in nonheme iron
increased liver iron level ( J:176655 )
• increase in nonheme iron

immune system
decreased spleen iron level ( J:176655 )
• decrease in nonheme iron

liver/biliary system
increased liver iron level ( J:176655 )
• increase in nonheme iron

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory