Phenotypes Associated with This Genotype

Genotype
MGI:5294615

• Allelic Composition: Col1a1^{tm3(tetO-Mirlet7g/Mir21)Gqda}/Col1a1⁺; Gt(ROSA)26Sor^{tm1(rtTA*M2)Jae}/Gt(ROSA)26Sor⁺
• Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:177113 )

• following doxycycline treatment

postnatal growth retardation ( J:177113 )

• following doxycycline treatment

homeostasis/metabolism

increased circulating glucose level ( J:177113 )

• in the fed state following doxycycline treatment

increased circulating insulin level ( J:177113 )

• during a glucose tolerance test in doxycycline treated mice

• however, no difference in insulin sensitivity is detected following doxycycline treatment

impaired glucose tolerance ( J:177113 )

• following doxycycline treatment on a normal or high fat diet