Phenotypes Associated with This Genotype

Genotype
MGI:5292475

• Allelic Composition: Irx3^tm1Hui/Irx3^tm1Hui
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal atrioventricular bundle conduction ( J:175992 )

• increase of the conduction time between the His bundle and ventricles

• right bundle branch block

abnormal heart electrocardiography waveform feature ( J:175992 )

• display ventricular activation defects at 2 weeks of age

abnormal QRS complex ( J:175992 )

• right axis deviation, detected as a negative QRS deflection in lead I combined with a positive deflection in lead II, is observed in 70% of mice

prolonged QRS complex duration ( J:175992 )

abnormal R wave ( J:175992 )

• notched R wave