Phenotypes Associated with This Genotype

Genotype
MGI:5285659

• Allelic Composition: Met^tm1Cpo/Met^tm1Cpo
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:174591 )

N • mice exhibit normal numbers of motor neurons in the spinal cord

abnormal axon extension ( J:174591 )

• cutaneous maximus nerves exhibit pronounced axonal growth defects compared with wild-type nerves

abnormal neuron physiology ( J:174591 )

• cultured motor neurons fail to exhibit an effect on neuron survival in response to HGF treatment compared with similarly treated wild-type mice

cellular

abnormal axon extension ( J:174591 )

• cutaneous maximus nerves exhibit pronounced axonal growth defects compared with wild-type nerves