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Phenotypes Associated with This Genotype
Genotype
MGI:5285193
Allelic
Composition		 Cdkn1atm1Hpw/Cdkn1a+
Trp53tm2Wahl/Trp53tm2Wahl
Genetic
Background		 involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn1atm1Hpw mutation (1 available); any Cdkn1a mutation (60 available)
Trp53tm2Wahl mutation (0 available); any Trp53 mutation (232 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased mortality induced by ionizing radiation ( J:174375 )
• compared with irradiated Trp53tm2Wahl homozygotes

homeostasis/metabolism
decreased mortality induced by ionizing radiation ( J:174375 )
• compared with irradiated Trp53tm2Wahl homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory